International Registry of Stem Cell Treatment Providers  ·  2026 Clinical Edition  ·  1,508 Verified Clinics Across 73 Countries
StemCell Registry
Global Clinical Directory
1,508 Providers
73 Countries
Edition 2026
FAQ
StemCell RegistryUSAPennsylvania › The Center for Sports Medicine & Wellness (Regenexx)

The Center for Sports Medicine & Wellness (Regenexx)

A non-surgical sports and spine practice led by Dr Brian Shiple, offering platelet and cell injections; its site states the Glen Mills, Pennsylvania clinic has closed and relocated to Florida.

Medical Disclaimer: This profile is compiled for informational purposes only and is not medical advice, a clinical endorsement, or a statement that any treatment is proven or approved. Stem cell therapies vary widely in regulatory status and evidence. Consult a qualified physician before pursuing treatment.

Overview

The Center for Sports Medicine and Wellness is the practice of Dr Brian J. Shiple, a non-surgical sports and spine medicine physician. Anyone using this directory should read the site's own notice first: it states that Dr Shiple has closed his Pennsylvania interventional regenerative sports and spine medicine practice and relocated to south-west Florida, now operating as Integrative Rehab Medicine in Estero, Florida. The former Pennsylvania address given is 1788 Wilmington Pike, Suite 2000, Glen Mills, Pennsylvania, telephone 610-459-4200; the Florida number given is 239-687-3199.

The practice is orientated entirely around avoiding surgery. The site describes the physician as a specialist in minimally invasive, non-operative technology for orthopaedic and sports medicine, and lists his credentials as DO (doctor of osteopathic medicine), CAQSM (certificate of added qualification in sports medicine) and RMSK (registered musculoskeletal sonographer). It names several proprietary or branded procedures, including the DiscSeel procedure for spinal discs, treatments the practice calls Spine Renu and JointRenu, Tenex tenotomy for tendon problems, and ultrasound-guided nerve hydrodissection.

The cell-based treatments the site names divide along an important line. For the Pennsylvania practice it lists platelet rich plasma (PRP, concentrated from a sample of the patient's own blood), bone marrow concentrate from the patient's own marrow, alpha-2 macroglobulin (A2M, a protein concentrated from the patient's own blood), autologous stem cell injections and adipose fat grafts — all autologous, meaning taken from the patient's own body. For the Florida practice it additionally lists stromal vascular fraction from fat, exosomes, placental tissue products, umbilical cord stem cells and amniotic membrane grafts — these last categories are allogeneic, meaning derived from donated birth tissue rather than from the patient.

That difference matters to a prospective patient, because donor birth-tissue and exosome products raise distinct questions about sourcing, processing and regulatory status that autologous preparations do not. The site does not name the tissue supplier for the donor-derived products, publish any certificate of analysis, give prices, state a founding year or mention languages. A prospective patient would need to establish which location they would actually be treated at, what product would be used and who supplies it.

At a Glance

Location
Glen Mills, Pennsylvania, USA
Google Rating
5 ★ (67 reviews)
Established
The site does not state a founding year.
Languages
The site does not state any languages offered.

Services and Treatments Offered

  • Platelet rich plasma (PRP) injections
  • Bone marrow concentrate injections
  • Alpha-2 macroglobulin (A2M) injections
  • Autologous stem cell injections
  • Adipose (fat) grafting
  • Stromal vascular fraction injections (Florida practice)
  • Exosome treatments (Florida practice)
  • Placental tissue, umbilical cord and amniotic membrane products (Florida practice)
  • DiscSeel procedure for spinal discs
  • Spine Renu and JointRenu procedures
  • Tenex tenotomy for tendon problems
  • Ultrasound-guided nerve hydrodissection

Conditions Treated

The site organises its information by body region and lists the following.

Knee meniscus tears, osteoarthritis and patellar tendonitisDegenerative disc disease, herniated discs, annular tears and sciaticaRotator cuff tears, shoulder arthritis, bursitis and nerve impingementAchilles tendon injuries, plantar fasciitis and Morton's neuromaTennis elbow and cubital tunnel syndromeCarpal tunnel syndrome and ulnar neuropathySports injuries

Cell Sources and Technologies

The site states that the Pennsylvania practice used only the patient's own tissue — platelets, bone marrow concentrate, a blood protein concentrate and fat grafts — while the Florida practice additionally offers donor-derived birth tissue and exosome products.

Bone marrow concentrate — autologous (from the patient's own body), drawn from the patient's bone marrowAdipose (fat) graft and stromal vascular fraction — autologous, prepared from the patient's own fat tissuePlatelet rich plasma (PRP) and alpha-2 macroglobulin (A2M) — autologous, prepared from a sample of the patient's own bloodUmbilical cord stem cells, placental tissue products and amniotic membrane grafts — allogeneic (from a donor), derived from donated birth tissue; listed for the Florida practiceExosomes — listed for the Florida practice; the site does not state their origin or supplierThe site does not name the tissue bank supplying the donor-derived products and publishes no certificate of analysis.

Physicians and Clinical Team

One physician leads the practice.

Brian J. Shiple — DO, CAQSM, RMSK; founder and principal physician, described as a specialist in minimally invasive, non-operative orthopaedic and sports medicineSebastian Klisiewicz — named on the site as a collaborator at the Florida practice

Facility and Patient Experience

The site describes an office-based practice carrying out ultrasound-guided injection, percutaneous tendon procedures and disc procedures, with no operating theatre described. Opening hours given are Monday to Thursday 8.30am to 4.30pm and Friday 8.30am to 1pm. The critical point is location: the site states the Glen Mills, Pennsylvania clinic at 1788 Wilmington Pike, Suite 2000 has closed, with the practice relocated to Estero, Florida under the name Integrative Rehab Medicine.

  • Site states the Glen Mills, Pennsylvania clinic has closed and the practice has relocated to Estero, Florida
  • Former Pennsylvania address: 1788 Wilmington Pike, Suite 2000, Glen Mills, Pennsylvania; telephone 610-459-4200
  • Florida practice operates as Integrative Rehab Medicine; telephone 239-687-3199
  • Office hours given as Monday to Thursday 8.30am to 4.30pm, Friday 8.30am to 1pm
  • Ultrasound-guided injection and percutaneous procedures carried out in the office
  • Physician holds a registered musculoskeletal sonographer (RMSK) certification
  • No laboratory accreditation or tissue supplier named
  • No languages other than English stated

Cost and Payment

The site publishes no prices and makes no statement about insurance coverage. A prospective patient would need to ask directly, and should establish at which location they would be treated before discussing cost.

Profile compiled from information published on the clinic's own website and from the StemCell Registry directory record. Details may change; confirm directly with the clinic before making decisions.

Other Providers in Pennsylvania

View all providers in Pennsylvania →