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StemCell RegistryUSAMinnesota › Mayo Clinic - Regenerative Medicine Program

Mayo Clinic - Regenerative Medicine Program

The regenerative medicine work of Mayo Clinic, a large academic medical system, combining ultrasound-guided platelet and bone marrow injections with research and clinical trials.

Medical Disclaimer: This profile is compiled for informational purposes only and is not medical advice, a clinical endorsement, or a statement that any treatment is proven or approved. Stem cell therapies vary widely in regulatory status and evidence. Consult a qualified physician before pursuing treatment.

Overview

Mayo Clinic's regenerative medicine work runs on two tracks, and the difference matters. On the patient side, Mayo Clinic Orthopedics and Sports Medicine runs a regenerative sports medicine service offering injection treatments in clinic. Separately, the Center for Regenerative Biotherapeutics is a research and biomanufacturing body, which the site describes as translating discoveries into early-phase clinical trials rather than running a treatment service of its own.

The clinical service describes minimally invasive, ultrasound-guided procedures carried out under local anaesthetic. Two treatments are named. For platelet rich plasma (PRP, prepared from the patient's own blood), platelets are isolated and concentrated and then injected into the injured area; the site states that it operates a quality control programme to keep preparations consistent, which is a detail most clinics do not mention. For bone marrow aspirate concentrate, marrow is taken from the pelvic bone, concentrated and injected into the damaged tissue. Both are autologous — taken from the patient's own body — and no donor, umbilical cord or amniotic product is named.

The conditions named are musculoskeletal: Achilles and patellar tendon injuries, tennis and golfer's elbow, plantar fasciitis, ligament sprains, arthritis and meniscal injuries. The service is described as research-based with many ongoing clinical trials available. The research centre's own stated focus areas are immunotherapy for cancer and other illness, transplant innovation, and surgical and procedural innovation, with engineered cell therapy, tissue engineering and bioprinting named as capabilities. No outcome figures or success rates appear on the pages reviewed.

Injection appointments are listed at five sites: Rochester and Minneapolis in Minnesota, two in Tempe, Arizona, and Jacksonville, Florida. The Center for Regenerative Biotherapeutics is based at 200 First Street SW, Rochester. No costs are published and nothing is said about insurance cover for these injections, so a prospective patient would need to ask both what is charged and whether a clinical trial route might apply to their condition. No languages or founding dates appear on the pages reviewed.

At a Glance

Location
Rochester, Minnesota, USA
Address
mayoclinic.org (Regenerative Medicine)
Google Rating
4.7 ★ (18 reviews)

Services and Treatments Offered

  • Platelet rich plasma (PRP) injections, ultrasound-guided and under local anaesthetic
  • Bone marrow aspirate concentrate injections, with marrow taken from the pelvic bone
  • Clinical trials of regenerative therapies
  • Engineered cell therapy and tissue engineering research, including bioprinting
  • Biomanufacturing of advanced biotherapies for early-phase clinical trials

Conditions Treated

The injection service names musculoskeletal problems; the research centre's interests are much broader.

Achilles tendon injuryPatellar tendon injury (jumper's knee)Tennis elbow and golfer's elbowPlantar fasciitisLigament sprainsArthritisMeniscal injuriesCancer and other illnesses (research focus of the Center for Regenerative Biotherapeutics)Transplant-related problems (research focus)

Cell Sources and Technologies

The clinical service describes both of its preparations as coming from the patient: platelets concentrated from blood, and bone marrow aspirated from the pelvis and concentrated.

Platelets — autologous (from the patient's own body), isolated and concentrated from the patient's blood, with a quality control programme stated on the siteBone marrow aspirate concentrate — autologous, with marrow taken from the pelvic bone and concentratedNo donor (allogeneic), umbilical cord or amniotic products are named for the clinical injection serviceThe research centre separately works on engineered cell therapies and tissue engineering; these reach patients through clinical trials rather than as purchasable treatments

Physicians and Clinical Team

The injection service page names no individual clinicians; two researchers are mentioned as examples on the research centre's page.

No clinicians are named on the regenerative sports medicine service pageKeith L. Knutson, PhD — named on the research centre's page as an example of its researchersMatthew S. Block, MD, PhD — named on the research centre's page as an example of its researchers

Facility and Patient Experience

This is a service inside a large academic medical centre rather than a standalone clinic. Injection appointments are listed at five sites — Rochester and Minneapolis in Minnesota, two locations in Tempe, Arizona, and Jacksonville, Florida — with procedures performed in clinic under ultrasound guidance and local anaesthetic. The Center for Regenerative Biotherapeutics at 200 First Street SW, Rochester, is described as Mayo's biomanufacturing hub, which means cell products for trials are made in-house rather than bought in. The site also states that there is a quality control programme for platelet preparations.

  • Injection service telephone numbers listed: Rochester, Minnesota 507-266-9100; Minneapolis 612-313-0520; Tempe, Arizona 480-574-2900 and 480-342-6800; Jacksonville, Florida 904-953-0305
  • Center for Regenerative Biotherapeutics address: 200 First Street SW, Rochester, Minnesota 55905
  • Part of Mayo Clinic, with access to its imaging, surgical and specialist services
  • Procedures described as minimally invasive, ultrasound-guided and performed under local anaesthetic
  • On-site biomanufacturing for early-phase clinical trials, described as Mayo's biomanufacturing hub
  • The site states there is a quality control programme for platelet preparations
  • Many ongoing clinical trials are said to be available
  • No accreditation details or languages are stated on the pages reviewed

Cost and Payment

No prices appear on the pages reviewed, and nothing is said about whether insurance covers these injections. Because the service is research-linked, it is worth asking both what a self-pay injection would cost and whether an open clinical trial might cover the treatment instead.

Profile compiled from information published on the clinic's own website and from the StemCell Registry directory record. Details may change; confirm directly with the clinic before making decisions.

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