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StemCell RegistryItaly › Ospedale San Raffaele Research Hospital

Ospedale San Raffaele Research Hospital

A large research and teaching hospital in Milan whose haematology units carry out blood stem cell transplants, CAR-T cell therapy and approved gene therapy for children and adults.

Medical Disclaimer: This profile is compiled for informational purposes only and is not medical advice, a clinical endorsement, or a statement that any treatment is proven or approved. Stem cell therapies vary widely in regulatory status and evidence. Consult a qualified physician before pursuing treatment.

Overview

IRCCS Ospedale San Raffaele is a large research and teaching hospital at Via Olgettina 60 in Milan. The letters IRCCS stand for Istituto di Ricovero e Cura a Carattere Scientifico, the Italian designation for a hospital recognised by the state for scientific research alongside clinical care. It is a general hospital with many departments, not a private cell therapy clinic, and it is listed here for its established cell therapy and transplant programmes.

The hospital's haematology and bone marrow transplant unit states that it performs haematopoietic stem cell transplants — that is, transplants of the blood-forming stem cells found in bone marrow. Its page describes autologous transplants (using the patient's own cells), allogeneic transplants (using a donor's cells) and haploidentical transplants (using a half-matched family donor). The same unit states that it provides CAR-T cell therapy, in which a patient's immune cells are modified in a laboratory before being returned, and gene therapy. It gives figures of about 150 transplants and 20 CAR-T treatments each year.

A separate paediatric immunohaematology unit states that it performs haematopoietic stem cell transplants in children using matched family donors, half-matched family donors and unrelated registry donors, and that it delivers approved gene therapy for adenosine deaminase deficient severe combined immunodeficiency, a rare inherited immune disorder. Its page states that 110 children have been treated with gene therapy based on blood-forming stem cells, and that clinical trials continue in beta thalassaemia, Wiskott-Aldrich syndrome and metachromatic leukodystrophy.

This is hospital medicine delivered through specialist units and, in several of the areas above, through clinical trials. Access is by referral into the relevant unit rather than by direct booking, and the site publishes no price list. Prospective patients should note that gene therapy and CAR-T work described here applies to specific named disorders and is not offered as a general treatment.

At a Glance

Location
Milan, Lombardy, Italy
Address
Via Olgettina 60, 20132 Milan | One of the largest research hospitals in Europe
Google Rating
2.3 ★ (258 reviews)

Services and Treatments Offered

  • Haematopoietic stem cell transplant, autologous (using the patient's own cells)
  • Haematopoietic stem cell transplant, allogeneic (using a donor's cells)
  • Haploidentical transplant using a half-matched family donor
  • CAR-T cell therapy, in which immune cells are modified in a laboratory before being returned to the patient
  • Gene therapy based on blood-forming stem cells, including an approved treatment for adenosine deaminase deficient severe combined immunodeficiency
  • Paediatric stem cell transplant using family, half-matched and unrelated registry donors
  • Clinical trials in gene therapy for inherited disorders
  • Day hospital and outpatient haematology care

Conditions Treated

The hospital's haematology and paediatric immunohaematology units name the following among the conditions they treat.

Acute leukaemiasMyeloproliferative neoplasmsMyelodysplastic syndromesMultiple myelomaLymphomasBone marrow aplasiaThalassaemia syndromes, including beta thalassaemiaSickle cell diseaseAutoimmune conditionsSelected solid tumoursAdenosine deaminase deficient severe combined immunodeficiencyWiskott-Aldrich syndromeMetachromatic leukodystrophy

Cell Sources and Technologies

The hospital states that its cell therapy work is transplant and gene therapy medicine in haematology — blood-forming stem cells and laboratory-modified immune cells for named blood, immune and inherited disorders — rather than injections for general musculoskeletal or cosmetic complaints.

Haematopoietic stem cells, autologous — the site states these come from the patient's own body and are returned after treatment.Haematopoietic stem cells, allogeneic — the site states these come from a donor, including matched family donors, half-matched (haploidentical) family donors and unrelated donors from a registry.Genetically modified haematopoietic stem cells — the site states these are the patient's own blood-forming stem cells altered in a laboratory before being returned, used in approved gene therapy and in trials.CAR-T cells — the site states these are immune cells modified in a laboratory to recognise cancer cells before being given back to the patient.

Physicians and Clinical Team

The hospital names the following among the clinicians leading its cell therapy and transplant units.

Professor Fabio Ciceri — director of the haematology and bone marrow transplant unitDr Piera Angelillo — haematologist, coordinator for CAR-T cell therapyDr Maria Teresa Lupo Stanghellini — haematologist, coordinator for allogeneic transplantProfessor Alessandro Aiuti — director of the paediatric immunohaematology unitDr Maria Ester Bernardo — paediatrician, coordinator for bone marrow transplant in childrenDr Maria Pia Cicalese — paediatrician, quality officer for the paediatric unit

Facility and Patient Experience

The hospital is a large campus at Via Olgettina 60 in the north-east of Milan, holding many clinical departments together with research institutes. The haematology unit's page places its inpatient ward in sector D on the second floor, its day hospital in sector Q1 on the second floor and its outpatient clinic in sector R on the lower ground floor, with secretariat hours of Monday to Friday, 8am to 3.30pm. The hospital carries the Italian IRCCS designation for a research hospital. The site does not state a founding year on the pages read.

  • Address: Via Olgettina 60, 20132 Milan, Italy
  • Haematology unit telephone: 02 2643 3903; day hospital 02 2643 3842
  • Paediatric immunohaematology unit secretariat telephone: 02 2643 4387
  • Haematology secretariat hours given as Monday to Friday, 8am to 3.30pm
  • Recognised as an IRCCS, the Italian designation for a hospital with a research remit
  • Inpatient ward, day hospital and outpatient clinic in separate sectors of the campus
  • Website published in Italian, with some English pages

Cost and Payment

The site publishes no prices for transplant, CAR-T or gene therapy. These are hospital services reached by clinical referral within the Italian health system, and the pages read give no indication of self-funded pricing.

Profile compiled from information published on the clinic's own website and from the StemCell Registry directory record. Details may change; confirm directly with the clinic before making decisions.